A decade of the anaphase-promoting complex in the nervous system.

Regulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS protein.

Glia mediate a vast array of cellular processes and are critical for nervous system development and function. Despite their immense importance in neurobiology, glia remain understudied and the molecular mechanisms that direct their differentiation are poorly understood. Rap/Fzr is the Drosophila homolog of the mammalian Cdh1, a regulatory subunit of the anaphase-promoting complex/cyclosome (APC...

O1: Modeling of Mesenchymal Stem Cell-Derived Magnetite Nanoparticles for The Rehabilitation of Immune System Function and Reducing Inflammation and Promoting Myelination in the Treatment of MS Disease

By Using the modeling of the mesenchymal (bone marrow) stem cell nanoparticles, the reinstatement of the immune system leads to the treatment of MS, result in the formation of a new immune system for the body by stem cell. The presence of stem cells promotes and strengthens myelination, and that, using simulation and 3D modeling, stem cells can be transmitted correctly to the target and place o...

P176: Neurological Diseases: Causes, Symptoms and Treatments

The nervous system is an extremely complex communication system that can send and receive large amounts of information simultaneously. The nervous system has two distinct parts: the central nervous system (the brain and the spinal cord) and the peripheral nervous system (the nerves located outside the brain and spinal cord). The main unit of the nervous system is neural cells (neurons). The rou...

APC/C Anaphase Promoting Complex/Cyclosome DUB deubiquitinase SAC spindle assembly checkpoint UPS ubiquitin-proteasome system

Central Nervous System Tumors in Guilan, Iran: Epidemiological Features Over 10 Years

Background: Tumors of the central nervous system (CNS) are a heterogeneous group of neoplasms with different prevalence in different sex and age groups and various parts of CNS. Objectives: Determining the relative frequency of different types of CNS tumors in different ages, sex and CNS anatomical locations. Materials and Methods: This retrospective study was performed using pathological repor...